Molecular Markers in Animal Genome Analysis

نویسنده

  • A. Teneva
چکیده

Over the last two decades advances in molecular genetics have introduced a new generation of molecular markers for the genetic improvement of livestock. This study is focused on the most advanced DNA-based molecular markers which have acted as versatile tools and have found their own position in various fields. Ever since their development, they are constantly being modified to enhance their utility and to bring about automation in the process of genome analysis. The discovery of PCR (polymerase chain reaction) was a milestone in this еndeavour and proved to be an unique process that brought about a new class of DNA profiling markers. In this article DNA-based molecular markers developed during the past decades restriction fragment length polymorphisms (RFLPs), microsatellites (SSRs), amplified fragment length polymorphism (AFLPs), single nucleotide polymorphisms (SNPs) for various applications in the area of animal genome analysis are reviewed.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Molecular identification of infertile bulls by using newly developed DDX3Y based on human STS markers

To determine the role of DDX3Y gene in spermatogenesis and infertility in bulls, blood samples were collected from five infertile bulls (azoospermic; no sperm in the semen) at the Animal Breeding Center in Karaj, Iran. The recommended human primers by EAA/EQMN were investigated using the BLASTn database for STS marker detection. Alignment of STS marker genes with bovine genome was performed. Pr...

متن کامل

Sequencing and Molecular Analysis of ATP 6 and ATP 8 of Mitochondrial Genome in Khorasanian Native Chickens

In order to perform breeding programs and improve production of native chickens, preserving genetic diversity in different areas of Iran is important due to the reduced available population. Genome sequencing is considered the most functional approach to determine the phylogeny relation between close populations. The aim of the present study was the evaluation of the phylogeny and genetic nucle...

متن کامل

Isolation and Characterization of Microsatellite Markers from Endangered Species (Camelus bactrianus)

Iranian bactrian camel (Camelus bactrianus) is an endangered livestock breed with distribution in northwest of Iran. Microsatellites are a powerful marker for animal genetic and cell line identification and population genetic study. In this study, after producing more than 40 Camelus bactrianus fibroblast cell lines, microsatellites loci from the genome of Iranian Camelus bactrianus cell lines ...

متن کامل

Transferability of barley microsatellite markers for assessing genetic relationships of wheat wild relatives of Triticum and Aegilops genera

Comparative genomics has revealed a high degree of collinearity between related species, which allows transferability of interspecies and intergenus   markers. The aim of this study was to examine the transferability of barley microsatellite markers among species of Triticum and Aegilops genus for determination of their genetic relationships. The experiments was carried out in faculty of agricu...

متن کامل

The Impact of Different Genetic Architectures on Accuracy of Genomic Selection Using Three Bayesian Methods

Genome-wide evaluation uses the associations of a large number of single nucleotide polymorphism (SNP) markers across the whole genome and then combines the statistical methods with genomic data to predict the genetic values. Genomic predictions relieson linkage disequilibrium (LD) between genetic markers and quantitative trait loci (QTL) in a population. Methods that use all markers simultaneo...

متن کامل

Molecular study of a consanguineous family with autosomal recessive mental retardation and speech disorder

Mental retardation (MR) is one of the most frequently found major genetic disorders around the world, affecting 1-3% of the people in the general population. The recent advancement in molecular biology and cytogenetic study has made possible the identification of new genes for a variety of genetic disorders including autosomal recessive MR. Recessive genetic disorders are common in Pakistan due...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2009